It was an astounding matchday of results, with the league table starting to take a funny shape heading into the colder months in England.
West Ham finally ended the Reds' unbeaten run, United's woes were compounded and Arsenal continued their resurgence as the Premier League nears a third of the way completed.
Team of the Week is a brand new series from Zero Striker where the top performers from each matchday are included in a rolling '4-3-3' team of the week squad that will chop and change regularly.
Let's see what effect this has on our rolling XI after another round of season 2021/22.
Tim Krul (Norwich City) - in for Edouard Mendy (Chelsea)
The Dutch veteran had a stonking game in between the sticks as the Canaries finally chalked up their first win of the season in what was bizarrely Daniel Farke's final game in charge.
Krul made six saves inside the box and made one high claim as Norwich somehow toppled the dangerous Brentford away from home in London.
RB: Trent Alexander-Arnold (Liverpool)
Despite his team losing their first game of the year, Alexander-Arnold shone for the Reds on a bad day at the office for Jurgen Klopp.
Trent Alexander-Arnold isn't your normal right-back 🚀 pic.twitter.com/Q9gsCilQRU
— ESPN UK (@ESPNUK) November 7, 2021
Trent scored a pin-point freekick to level things up before half-time before assisting Divock Origi in the closing stages for what was a consolation goal.
RCB: Cristian Romero (Tottenham) - in for Zanka (Brentford)
The Argentinian centre-half was steadfast at the back for Antonio Conte's first league game in charge of Tottenham.
Although Spurs couldn't make it count against the Toffees, Romero blocked four shots, made three tackles and made two clearances in a performance that would have impressed his new manager.
LCB: Ethan Pinnock (Brentford) - in for Thiago Silva (Chelsea)
Ethan Pinnock was effective as a left-sided centre-back for Thomas Frank's side despite going down to Norwich at home.
Pinnock made one key pass and kept Max Aarons and Kieran Dowell quiet in an admirable display for the Bees.
LB: Joao Cancelo (Manchester City) - in for Ben Chilwell (Chelsea)
The Portuguese firmed his status as arguably the best fullback in the world with a huge outing against crosstown rivals Manchester United.
Cancelo assisted Bernardo Silva for City's second goal and made four successful long balls as Guardiola's side terrorised their beleaguered arch-enemies.
RM: Connor Gallagher (Crystal Palace) - in for Mason Mount (Chelsea)
The Chelsea loanee once again put on a show for Patrick Vieira's side as Palace beat Wolverhampton 2-0 at Selhurst Park.
Gallagher got on the scoresheet in the 78th minute to seal the win for the Eagles, as well as making four key passes in a game that would have Thomas Tuchel salivating over when the youngster returns to Stamford Bridge.
CM: Kevin De Bruyne (Manchester City) - in for Naby Keita (Liverpool)
The Belgian maestro put in a shift in the Manchester Derby, running the show for Pep's men as they beat United 2-0 at the Theatre of Dreams.
'KDB' made four key passes and eight successful long balls out of ten attempts as City bounced back from their shock loss to Crystal Palace at home.
LM: Emile Smith Rowe (Arsenal)
The Arsenal youngster had another successful outing, this time as the Gunners toppled Claudio Ranieri's Watford.
Smith Rowe got on the scoresheet to make it four goals and two assists in ten league starts for Mikel Arteta's side, with the 21-year-old also earning his first England call-up from manager Gareth Southgate.
RW: Jarrod Bowen (West Ham) - in for Mohamed Salah (Liverpool)
The 24-year-old winger was on song for David Moyes' side as they toppled title contenders Liverpool at home 3-2.
Bowen chalked up two assists for the Irons, helping West Ham to a mind-boggling third place after eleven games played this season.
ST: Leandro Trossard (Brighton & Hove Albion) in for Joshua King (Watford)
Trossard's Brighton were humbled at home against Newcastle and were lucky not to lose after keeper Robert Sanchez was sent off in the 92nd minute.
The Belgian however had a great game for Graham Potter's side, winning and dispatching a penalty as well as making three key passes in a man-of-the-match display.
LW: Ainsley Maitland-Niles (Arsenal) - in for Phil Foden (Manchester City)
The Gunner's Swiss army knife stepped up for Arteta's side only months after voicing his annoyance at not being able to leave the North London side for more game-time.
Maitland-Niles was rock solid at central-midfield, making one key pass and winning seven of his eight ground duels to put himself into the conversation for a starting place in Arsenal's XI.