Western Sydney Wanderers 1 - 0 Brisbane Roar
A second half goal from GolGol Mebrahtu was all that could separate the two sides in what was a rematch of the 2014 A-League Grand Final. Brisbane arguably had the better of the first half but failed to find the back of the net. The Wanderers netted the only goal through 24-year-old Mebrahtu to cap a fairytale return to football. The former Melbourne Heart man was plying his first game back from a 12 month ACL injury. Romero Castelen played Mebrahtu through and he stroked it home past Jamie Young into the bottom corner. The Wanderers could have made it 2-0 a few minutes later after Borello conceded a penalty on the edge of the area. However, Mark Bridge had his penalty save by Young to keep Brisbane's hopes alive for another 15 minutes.
Central Coast Mariners 0 - 1 Wellington Phoenix
The Mariners will be kicking themselves after losing 1-0 thanks to a goalkeeping howler and a missed penalty. Paul Izzo's first game as a Mariner will be one to forget as his first touch from a back pass was too heavy and it allowed Appiah-Kubi to score the only goal of the match to see Wellington advance to the round of 0f 16. To make matters worse for the home side, new signing Roy O'Donovan hit the crossbar from a penalty in the 82nd minute that would have leveled the scores.
Newcastle Jets 2 - 2 Perth Glory (Perth won 4-3 on penalties)
This was an enthralling encounter between two sides fighting for redemption this season. The Glory need to move on from their salary cap breaches of last season and the Jets need to rebuild after a shocking season in 2014-15. The Jets took the early lead through David Carney after he pounced on an Anthony Golec mistake at the back. Newcastle looked to be headed into the round of 16, before the Glory equalised just two minutes from time through Sidnei Sciola. The game then went to extra time, with Nebo Marinkovic scoring from the penalty spot to give Perth the lead in the first half. Newcastle then brought scores level once again with Labinot Haliti scoring from close range from a brilliant David Carney cross. Perth then won the penalty shootout 4-3 to advance to the next round.
Oakleigh Cannons 1 - 1 Far North Queensland (Oakleigh won 5-4 on penalties)
The highly fancied Oakleigh outfit entered the match with five ex-A-League players in their side. However, the favourites couldn't find a way through in regulation time, with the match going to extra time with the scores locked at 0-0. Oakleigh then scored first in the 93rd minute through a sublime long range free kick from Dean Piemonte. Just when the match looked won, Far North Queensland equalised in the 119th minute through a fortuitous goal. Jamie Gosling shot from long range with the ball taking a high bounce just in front of goal keeper John Honos before finding its way into the back of the net. Oakleigh then won the penalty shoot out 5-4.