The EFL Cup quarter-final draw has been released following the eight round of 16 matches that took place over Wednesday and Thursday morning.
The marquee match-up of the round of 16 was the Manchester derby, as United hosted City for a chance to progress through to the last eight.
Juan Mata's second half strike was the difference, as United won 1-0 to hand Pep Guardiola his sixth consecutive result without a win, the worst run of his career to date.
Liverpool saw off Tottenham 2-1 while West Ham beat Chelsea by the same scoreline in two of the other big matches in the previous stage.
Only two games in the quarter finals see Premier League teams face each other, as Manchester United host the Hammers while Arsenal welcome Southampton to the Emirates.
Liverpool host Championship side Leeds United, while fellow Championship Newcastle travel to Hull in the final of the four quarter final fixtures.
All four games will be played on the week commencing November 28.
Full quarter-final line-up:
Liverpool v Leeds
Manchester United v West Ham
Hull v Newcastle
Arsenal v Southampton