LONDON, ENGLAND - APRIL 10: Arsene Wenger, Manager of Arsenal looks dejected from the bench during the Premier League match between Crystal Palace and Arsenal at Selhurst Park on April 10, 2017 in London, England. (Photo by Clive Rose/Getty Images)

Arsene Wenger's reign as Arsenal manager hangs by a thread following a 3-0 loss to Crystal Palace on Tuesday morning (AEST).

The Gunners dominated the game with over 72% possession however could only muster three shots on target compared to Palace's six as the Eagles claimed their first home win over Arsenal since 1979.

The loss meant it's the first time that Arsenal have lost four consecutive away games under Wenger following losses at West Brom, Liverpool and Chelsea. In fact, the Gunners have earned just four points from their last eight away games, a telling record with the London club now sitting seven points outside the top four.

Wenger has led the Gunners to a record 19 straight Champions League appearances, with a 20th consecutive showing in serious doubt with eight games to play.

The veteran manager acknowledged the magnitude of the loss but said the pressure on him is no different from what he is used to.

"Every defeat is a big worry. I've managed over 1,100 games for Arsenal and we're not used to that," Wenger told Sky Sports.

"It's a big worry. Unfortunately it is like that and we have to respond very quickly and not accept it.

Once again, Arsenal fans voiced their disappointment with Wenger and the players by chanting "you're not fit to wear the shirt", with the manager saying he understood their frustrations.

"I understand our fans are disappointed and we all are deeply tonight," Wenger. It's very worrying and disappointing the way we lost the game," he told the BBC.

"We lost too many duels and we paid for that.

"There is no obvious reason why. We prepared and everyone prepared well. It's difficult to explain just after the game.

"We are in a difficult position. The game tonight doesn't help."